A Phase III study to evaluate the safety and efficacy of intravitreal (IVT) injections of conbercept versus aflibercept in subjects with neovascular (wet) age-related macular degeneration (wAMD).
Both conbercept and aflibercept inhibit a protein (VEGF) that promotes the growth of the abnormal blood vessels characteristic of wAMD. Aflibercept is the active ingredient in Eylea, a drug that has already received market approval. Conbercept is thought to bind more specifically to VEGF, reducing the dosage required, and also has a longer half-life than other available treatments.
- Subjects age ≥ 50 years
- 1140 subjects total
- Study duration: 92 weeks
- Recruiting subjects who have never received treatment for wAMD
Those that qualify may receive study-related care from a board-certified physician at no cost, receive compensation for time and travel, and have access to potential new medication.
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